Causal-Inference

Seeking a summer research intern (EXPIRED)

Seeking one student for a summer internship project on Mendelian randomization.

Quantifying and addressing the prevalence and bias of study designs in the environmental and social sciences

We reviewed the prevalence of different study designs in environmental and social sciences and introduced a novel model for with-study comparisons.

Toward Better Practice of Covariate Adjustment in Analyzing Randomized Clinical Trials

This article proposes three principles for analyzing clinical trials based on a joint analysis of covariate adjustment in both the design and analysis stages.

A note on post-treatment selection in studying racial discrimination in policing

We discuss some causal estimands used to study racial discrimination in policing. A central challenge is that not all police-civilian encounters are recorded in administrative datasets and available to researchers. One possible solution is to …

Sensitivity analysis for observational studies

Sensitivity analysis is widely recognized as a critical step in an observational study but is seldom found in applications. One reason for its underuse is the various forms of model, inference, and interpretation in divergent literatures. This talk …

Using sparsity to overcome unmeasured confounding

Sparsity is often used to improve the interpretability of a statistical analysis and/or reduce the variance of a statistical estimator. This talk will explore another aspect—the utility of sparsity in model identifiability through two problems …

Mendelian randomization with coarsened exposures

A key assumption in Mendelian randomisation is that the relationship between the genetic instruments and the outcome is fully mediated by the exposure, known as the exclusion restriction assumption. However, in epidemiological studies, the exposure …

Bootstrapping sensitivity analysis

A latent mixture model for heterogeneous causal mechanisms in Mendelian randomization

There is a general lack of awareness that MR can be used to discover multiple biological mechanisms, partly due to the wide usage of the broad terminology 'effect heterogeneity' to refer to several different phenomena. This article introduces the concept of mechanistic heterogeneity and proposes a latent mixture model to make inference about the causal mechanisms.

Is this estimand really an average treatment effect?

This post is about an interesting causal (?) estimand that appears in studies of racially biased policing using adminstrative records.