John Aston

Journal Publications

Additional information can be found at my Google Scholar profile

* - indicates supervised MSc, PhD or PDRA


E Lila*, SR Arridge, JAD Aston. Representation and reconstruction of covariance operators in linear inverse problems, Inverse Problems, in press.

C Stoehr, JAD Aston, C Kirch. Detecting changes in the covariance structure of functional time series with application to fMRI data, Econometrics and Statistics, in press.

E Lila* and JAD Aston. Statistical Analysis of Functions on Surfaces with an application to Medical Imaging, Journal of the American Statistical Association, 115: 1420-1434.

N Debroux, JAD Aston, F Bonardi, A Forbes, CL Guyader, M Romanchikova, CB Schönlieb. A Variational Model Dedicated to Joint Segmentation, Registration, and Atlas Generation for Shape Analysis, SIAM Journal on Imaging Sciences, 13: 351-380


S Tavakoli*, D Pigoli*, JAD Aston and JS Coleman. Spatial modeling of Object Data: Analysing dialect sound variations across the UK (with discussion), Journal of the American Statistical Association, 114: 1081-1104.

A Kashlak*, JAD Aston and R Nickl. Inference on covariance operators via concentration inequalities: k-sample tests, classification, and clustering via Rademacher complexities, Sankyha A, 214-243

RM Ward, R Choudhary, Y Heo, and JAD Aston. A data-centric bottom-up model for generation of stochastic internal load profiles based on space-use type, Journal of Building Performance Simulation, 12:620--636

W Olszowy*, JAD Aston, C Rua, and GB Williams. Accurate autocorrelation modeling substantially improves fMRI reliability Nature Communications, 10: 1220, 1--11.

TA Pascoal, S Mathotaarachchi, MS Kang, S Mohaddes, M Shin, AY Park*, MJ Parent, AL Benedet, M Chamoun, J Therriault, H Hwang, AC Cuello, B Misic, J-P Soucy, JAD Aston, S Gauthier and P Rosa-Neto, Aβ-induced vulnerability propagates via the brain's default mode network. Nature Communications, 10: 2353, 1--13.

JAD Aston, F Autin, G Claeskens, JM Freyermuth* and C Pouet. Minimax optimal procedures for testing the structure of multidimensional functions, Applied and Computational Harmonic Analysis, 46: 288-311.


JAD Aston and C Kirch. Efficiency of change points tests in high dimensional settings, Electronic Journal of Statistics, 12: 1901-1947.

D Pigoli*, PZ Hadjipantelis*, JS Coleman and JAD Aston. The statistical analysis of acoustic phonetic data: exploring differences between spoken Romance languages (with discussion), Journal of the Royal Statistical Society, Series C, 67:1103-1145

Y Wang, B Dai, G Hua, JAD Aston and D Wipf. Recurrent Variational Autoencoders for Learning Nonlinear Generative Models in the Presence of Outliers IEEE Journal of Selected Topics in Signal Processing 12:1615--1627

B Dai, Y Wang, JAD Aston, G Hua, D Wipf. Connections with robust PCA and the role of emergent sparsity in variational autoencoder models, Journal of Machine Learning Research, 19:1573--1614.


H Sayal*, JAD Aston, D Elliott and H Ombao. An Introduction to Applications of Wavelet Benchmarking with Seasonal Adjustment, Journal of the Royal Statistical Society, Series A, 180:863-889.

JAD Aston, D Pigoli* and S Tavakoli*. Tests for separability in nonparametric covariance operators of random surfaces, Annals of Statistics, 45:1431-1461.

F Lindsten, AM Johansen, CA Naesseth, B Kirkpatrick, TB Schön, JAD Aston, and A Bouchard-Côté. Divide-and-Conquer with Sequential Monte Carlo, Journal of Computational and Graphical Statistics 26:445-458.

N Shiers*, JAD Aston, JQ Smith and JS Coleman. Gaussian tree constraints applied to acoustic linguistic functional data, Journal of Multivariate Analysis, 154:199-215.


E Lila*, JAD Aston, and LM Sangalli. Smooth Principal Component Analysis over two-dimensional manifolds with an application to Neuroimaging, Annals of Applied Statistics, 10: 1854 - 1879.

Y Zhou*, AM Johansen and JAD Aston. Towards Automatic Model Comparison: An Adaptive Sequential Monte Carlo Approach, Journal of Computational and Graphical Statistics, 25:701--726.

N Shiers*, P Zwiernik, JAD Aston and JQ Smith. The correlation space of Gaussian latent tree models and model selection without fitting, Biometrika, 103:531--545.

RV Belavkin, A Channon, E Aston, JAD Aston, R Krasovec, and CG Knight. Monotonicity of Fitness Landscapes and Mutation Rate Control, Journal of Mathematical Biology, 73: 1491-1524.

CR Jiang, JAD Aston and JL Wang. A functional approach to deconvolve dynamic neuroimaging data Journal of the American Statistical Association, 111:1-13.


PZ Hadjipantelis*, JAD Aston, HG Müller, and JP Evans. Unifying Amplitude and Phase Analysis: A Compositional Data Approach to Functional Multivariate Mixed-Effects Modeling of Mandarin Chinese, Journal of the American Statistical Association, 110:545--559.

CFH Nam*, JAD Aston, I Eckley and R Killick. The Uncertainty of Storm Season Changes: Quantifying the Uncertainty of Autocovariance Changepoints, Technometrics, 57:194--206.

AN Gott, IA Eckley and JAD Aston. Estimating the population local wavelet spectrum with application to non-stationary functional magnetic resonance imaging time series Statistics in Medicine 34:3901--3915.


PZ Hadjipantelis*, JAD Aston, HG Müller and J Moriarty. Analysis of spike train data: A multivariate mixed effects model for phase and amplitude. Electronic Journal of Statistics 8:1797--1807

R Krasovec, RV Belavkin, JAD Aston, A Channon, E Aston, B Rash, M Kadirvel, S Forbes and CG Knight. Mutation-rate-plasticity in rifampicin resistance depends on Escherichia coli cell-cell interactions, Nature Communications, 5:3742, 1--8.

D Pigoli*, JAD Aston, IL Dryden and P Secchi. Distances and Inference for Covariance Functions, Biometrika, 101:409--422.

CFH Nam*, JAD Aston, and AM Johansen. Parallel Sequential Monte Carlo Samplers and Estimation of the Number of States in a Hidden Markov Model, Annals of the Institute of Statistical Mathematics, 66:553--575.

G Minas*, JAD Aston and N Stallard. Adaptive multivariate global testing, Journal of the American Statistical Association, 109}:613--623.

Q Caudron*, C Lyn-Adams, JAD Aston, BG Frenguelli and KG Moffat. Quantitative Assessment of Ommatidial Distortion in Drosophila melanogaster, Drosophila Information Service, 96:136--144.


A Sorrentino*, AM Johansen, JAD Aston, TE Nichols and WS Kendall. Dynamic filtering of Static Dipoles in MagnetoEncephaloGraphy (2013), Annals of Applied Statistics, 7:955-988.

AJ Hall*, MJ Chappell, JAD Aston and SA Ward. Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin (2013), Computer Methods and Programs in Biomedicine, 112:1-15.

Y Zhou*, JAD Aston and AM Johansen. Bayesian Model Comparison for Compartmental Models with Applications in Positron Emission Tomography (2013), Journal of Applied Statistics, 40:993-1016.

DEK Martin and JAD Aston. Distribution of statistics of hidden state sequences through the sum-product algorithm (2013), Methodology and Computing in Applied Probability, 15:897-918.

I Hindrayanto, JAD Aston, SJ Koopman, M Ooms. Modeling trigonometric seasonal components for monthly economic time series (2013), Applied Economics, 45:3024-3034.


JAD Aston and C Kirch. Estimation of the distribution of change-points with application to fMRI data (2012), Annals of Applied Statistics, 6:1906-1948,

PZ Hadjipantelis*, JAD Aston and JP Evans. Characterizing fundamental frequency in Mandarin: A functional principal component approach utilizing mixed effect models (2012), Journal of the Acoustical Society of America, 131:4651-4664.

CFH Nam*, JAD Aston and AM Johansen. Quantifying uncertainty in change points (2012), Journal of Time Series Analysis, 33:807-823.

JAD Aston, JY Peng* and DEK Martin. Implied Distributions in Multiple Change Point Models (2012), Statistics and Computing, 22:981-993.

JAD Aston and C Kirch. Detecting and estimating changes in dependent functional data (2012), Journal of Multivariate Analysis, 109:204-220.

JAD Aston, D Buck, J Coleman, CJ Cotter, NS Jones, V Macaulay, N MacLeod, JM Moriarty and A Nevins (The Functional Phylogenies Group). Phylogenetic inference for function-valued traits: speech sound evolution (2012), Trends in Ecology and Evolution, 27:160-166.

G Minas*, F Rigat, TE Nichols, JAD Aston and N Stallard. A hybrid procedure for detecting Global Treatment Effects in Multivariate Clinical Trials: Theory and Applications to fMRI Studies (2012), Statistics in Medicine, 31:253-268.

DV Vavoulis, VA Straub, JAD Aston and J Feng. A Self-Organising State-Space-Model Approach for Parameter Estimation in Hodgkin-Huxley-
Type Models of Single Neurons (2012), PLoS Computational Biology, 8:3 e1002401, 1--31.


W-C Chi, WHK Lee, CJ Lin, JAD Aston, and CC Liu. Inversion of Ground Motion Data from a Seismometer Array for Rotation using a Modification of Jeager's Method (2011) Bulletin of the Seismological Society of America, 101:3105-3109.

JY Peng* and JAD Aston. The State Space Models Toolbox for MATLAB (2011) Journal of Statistical Software, 41:6 1-26.

JY Peng*, JAD Aston and C-Y Liou. Modeling Time Series and Sequences using Markov Chain Embedded Finite Automata (2011), Journal of Innovative Computing, Information and Control, 7:407-431.


PE Cheng, M Liou and JAD Aston. Likelihood Ratio Tests in Three-Way Tables (2010), Journal of the American Statistical Association, 105:740-749. [PDF]

JP Evans, M Chu, JAD Aston and C Su. Linguistic and human effects on F0 in a tonal dialect of Qiang (2010), Phonetica, 67: 82-99. [Data - please cite the paper and grant no. NSC (Taiwan) 95-2411-H-001-077 if used in publication]

RH Wang, JAD Aston, and CD Fuh. The Role of New Information in Option Pricing: Estimation Issues for the State Space Model (2010), Computational Economics, 36: 283-307.

JAD Aston, J-M Chiou and JP Evans. Linguistic Pitch Analysis using Functional Principal Component Mixed Effect Models (2010) Journal of the Royal Statistical Society, Series C (Applied Statistics), 59:297-317. [PDF] [Data - please cite the paper and grant no. NSC (Taiwan) 95-2411-H-001-077 if used in publication]


C-R Jiang, JAD Aston, and J-L Wang. Smoothing Dynamic Positron Emission Tomography Time Courses Using Functional Principal Components. (2009) Neuroimage, 47: 184-193.

J-D Lee, HR Su, PE Cheng, M Liou, CH Tsai, JAD Aston and CY Chen. Brain MR Image Segmentation using the Power Transformation Approach. (2009) IEEE Transactions on Medical Imaging, 28: 894-905.

M Liou, H-R Su, J-D Lee, A Savostyanov, JAD Aston, C-H Chuang and PE Cheng. Beyond p-values: Averaged and Reproducible evidence in fMRI experiments. (2009) Psychophysiology, 46: 367-378.


JAD Aston, EN Brown, WL Loh, KJ Worsley and Y Wu. Highlights - The Interface of Statistics and Brain Science. (2008) Statistica Sinica, 18:1201-1202.

JAD Aston, CD Fuh and SF Luo. Discussion on ``Is Average Run Length to False Alarm Always an Informative Criterion?" by Yajun Mei. Sequential Analysis, 27:381-384.

MJY Peng*, JAD Aston, RN Gunn, CY Liou and J Ashburner. Dynamic Positron Emission Tomography Data-Driven Analysis Using Sparse Bayesian Learning. (2008) IEEE Transactions on Medical Imaging, 27:1356-1369.

DEK Martin and JAD Aston. Waiting Time Distribution of Generalized Later Patterns. (2008) Computational Statistics and Data Analysis, 52:4879-4890. [CRiSM Research Report 08-11]

PE Cheng, M Liou, JAD Aston and AC Tsai. Information Identities and Testing Hypotheses: Power Analysis for Contingency Tables. (2008) Statistica Sinica, 18:535-558.



JAD Aston and DEK Martin. Distributions Associated with General Runs and Patterns in Hidden Markov Models (2007) Annals of Applied Statistics, 1:585-611. [PDF]

PE Cheng, JW Liou, M Liou, and JAD Aston. Linear Information Models: An Introduction. (2007) Journal of Data Science, 5:297-313



PE Cheng, JW Liou, M Liou, and JAD Aston. Data Information in Contingency Tables: A Fallacy of Hierarchical Loglinear Models. (2006) Journal of Data Science, 4:387-398.

JAD Aston and SJ Koopman. A non-Gaussian generalisation of the Airline model for robust Seasonal Adjustment (2006) Journal of Forecasting, 25:325-349.

FE Turkheimer, JAD Aston, M-C Asselin, and R Hinz. Multi-resolution Bayesian Regression in PET Dynamic Studies using Wavelets.(2006) Neuroimage, 32:111-121.

JAD Aston, FE Turkheimer and M Brett. HBM FIAC data analysis in wavelet space.(2006) Human Brain Mapping, 27:372-379. [Software]

M Liou, HR Su, J-D Lee, JAD Aston, AC Tsai and PE Cheng. A Method for Generating Reproducibility Evidence in fMRI studies. (2006) Neuroimage, 29:383-395.



JAD Aston and DEK Martin. Waiting Time Distributions of Competing Patterns in Higher-Order Markovian Sequences (2005) Journal of Applied Probability, 42:977-988.

JAD Aston and RN Gunn. Statistical Estimation with Kronecker Products in Positron Emission Tomography. (2005) Linear Algebra and its Applications, 398:25-36.

JAD Aston, RN Gunn, R Hinz, and FE Turkheimer. Wavelet Variance Components in Image Space for Spatiotemporal Neuroimaging Data. (2005) Neuroimage, 25:159-168.



FE Turkheimer, JAD Aston, and VJ Cunningham. On the logic of hypothesis testing in functional imaging. (2004) European Journal of Nuclear Medicine, 31:725-732.

FE Turkheimer, R Hinz, RN Gunn, JAD Aston, SR Gunn, and VJ Cunningham. Rank-shaping regularization of exponential spectral analysis for application to functional parametric mapping. (2003) Physics in Medicine and Biology, 48:3819-3841.

MH Beauchamp, A Dagher, JAD Aston and J Doyen. Dynamic functional changes associated with cognitive skill learning of an adapted version of the Tower of London task. (2003) Neuroimage, 20:1649-1660.

FE Turkheimer, JAD Aston, RB Banati, C Riddell, and VJ Cunningham. A linear wavelet filter for parametric imaging with dynamic PET. (2003) IEEE Transactions on Medical Imaging 22:289-301.

RN Gunn, SR Gunn, FE Turkheimer, JAD Aston, and VJ Cunningham. Positron Emission Tomography Compartmental Models: A Basis Pursuit Strategy for Kinetic Modeling. (2002) Journal of Cerebral Blood Flow and Metabolism, 22(12):1425-1439.

JAD Aston, VJ Cunningham, M-C Asselin, A Hammers, AC Evans, RN Gunn. Partial Volume Correction: Estimation and Algorithms (2002). Journal of Cerebral Blood Flow and Metabolism, 22(8):1019-1034.

CH Liao, KJ Worsley, JB Poline, JAD Aston, GH Duncan, AC Evans. Estimating the delay of the fMRI response (2002). Neuroimage 16(3):593-606.

KJ Worsley, C Liao, JAD Aston, V Petre, GH Duncan, AC Evans. A general statistical analysis for fMRI data (2002). Neuroimage 15(1):1-15.

A Dagher, C Bleicher, JAD Aston, RN Gunn, PBS Clarke, P Cumming. Reduced dopamine D1 receptor binding in the ventral striatum of cigarette smokers (2001). Synapse 42(1):48-53.

FE Turkheimer, M Brett, JAD Aston, AP Leff , PA Sargent, RJS Wise, PM Grasby, VJ Cunningham. Statistical modeling of positron emission tomography images in wavelet space (2000). Journal of Cerebral Blood Flow and Metabolism 20(11): 1610-1618.

JAD Aston, RN Gunn, KJ Worsley, Y Ma, AC Evans, A Dagher. A statistical method for the analysis of positron emission tomography neuroreceptor ligand data. (2000) Neuroimage 12(3): 245-256.

FE Turkheimer, RB Banati, D Visvikis, JAD Aston, RN Gunn, VJ Cunningham. Modeling dynamic PET-SPECT studies in the wavelet domain. (2000) Journal of Cerebral Blood Flow and Metabolism 20(5): 879-893.